Efficacy of G-CSF in the Management of Steroid Non-responsive Severe Alcoholic Hepatitis
Status:
Completed
Trial end date:
2017-06-01
Target enrollment:
Participant gender:
Summary
After successful screening, first the investigators first treat patients of severe alcoholic
hepatitis with steroids for 7 days. Patients who are found to be unresponsive as per Lille's
score [>0.45] would be randomized into either placebo group or G-CSF group. Responders to
steroids will continue on steroids for 28 days followed by 2 weeks of tapering. Non
responders will be randomized to receive G-CSF for 28days.