Efficacy of High-dose Dual Therapy vs Bismuth-containing Quadruple Therapy for First-line Treatment of Hp Infection
Status:
Completed
Trial end date:
2018-05-01
Target enrollment:
Participant gender:
Summary
Up to now, there is few randomized, large scale study prospectively and simultaneously
comparing the efficacy, adverse effects and patient adherence of high-dose dual therapy
(HDDT) and bismuth-containing quadruple therapy (BQT) as 1st-line regimens for H. pylori
eradication.
The aims of this study are:
1. to compare the efficacy of HDDT, and BQT as 1st-line regimen in H. pylori eradication;
2. to compare the patient adherence and adverse effects of these treatment regimens;
3. to investigate factors that may influence H. pylori eradication by these treatment
regimens.