Efficacy of IV Acetaminophen Versus Oral Acetaminophen

• Status: Recruiting
• Trial end date: 2021-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to determine whether intravenous acetaminophen compared to enteric acetaminophen offers increased efficacy in patients who are scheduled for laparoscopic donor nephrectomy and for patients scheduled for robot-assisted, laparoscopic nephrectomy for renal cancer at the University of Rochester Medical Center. The standard surgical and post-operative care, including post-operative pain management will not be altered.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Rochester
• Treatments: Acetaminophen

Criteria

Inclusion Criteria:

• Be at least 18 years old

• Be scheduled for donor nephrectomy or robot-assisted, laparoscopic nephrectomy for cancer at University of Rochester Medical Center

• Have cognitive ability to verbally rate their pain on the Numeric Rating Scale (NRS).

Exclusion Criteria:

• Age younger than 18 years old or older than 90 years old

• Pregnancy (Pre-operative pregnancy test is standard of care for all elective operating room cases)

• Weight less than 50 kg

• Anticipated surgical case duration greater than 5 hours

• Epidural use

• History of known liver disease.

• Patient unable to take enteral medications.

• Be taking opioid medications chronically.