Efficacy of IV Lidocaine at Alleviating Pain Associated With Propofol Infusion in Pediatric Patients Undergoing Sedation
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
This protocol describes a double-blind, placebo-controlled trial intended to demonstrate the
effectiveness of lidocaine at reducing pain associated wiht propofol infusion for short-term
deep sedation in children. Patients will be randomized to receive either placebo (saline) or
one of two dosing regimens of IV lidocaine prior to initiating propofol infusion. The
efficacy of the differing lidocaine doses will be compared to determine the minimum dose
required to safely achieve alleviation of pain. We hypothesize that premedicating with
lidocaine will significantly decrease pain experienced by pediatric patients receiving
propofol for outpatient sedation.