Efficacy of Intra-auricular Tranexamic Acid in Total Knee Arthroplasty
Status:
Completed
Trial end date:
2020-01-09
Target enrollment:
Participant gender:
Summary
Tranexamic acid an antifibrinolytic that develops its anti-haemorrhagic action by inhibiting
fibrinolytic activities of plasmin and many studies confirms its effectiveness in decreasing
blood loss. The aim of this study was to observe postoperative bleeding with combined
intravenous and per - os administration with two intra - articular doses (1 g and 2 g) of
tranexamic acid in adult patients undergoing unilateral total knee replacement.