Efficacy of Intralesional Bleomycin Alone and in Combination With Dexamethasone in Infantile Haemangiomas

• Status: Completed
• Trial end date: 2022-03-20
• Target enrollment: 0
• Participant gender: All

Summary

Objective:

This study is intended to compare the outcome of intralesional bleomycin with dexamethasone versus the bleomycin alone in infantile haemangioma.

Materials and Methods:

This RCT was performed after the ethical approval at the pediatric surgery department of KEMU/Mayo hospital Lahore. 114 patients were enrolled in two groups A and B. Both groups contained 57 patients each. Group A was administered intralesional bleomycin with dexamethasone and group B was given intralesional bleomycin alone with a space of 4 weeks. Selection of patients was made according to inclusions and exclusion criteria.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: King Edward Medical University
• Treatments: Bleomycin; Dexamethasone

Criteria

Inclusion Criteria:

• Patients with haemangioma with size equal or more than 1 c

• Less than 12 years and above 1 month of age.

Exclusion Criteria:

• Patients with previous surgical procedure for haemangiomas

• Patients with chronic respiratory conditions confirmed by history, symptoms and physical examination.

• The diagnosed case of pulmonary fibrosis.

• Patients sensitive to bleomycin proved upon giving a test dose