Efficacy of Intralesional PRP +/- Topical Silymarin in the Treatment of Melasma
Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Melasma is an acquired disorder of melanogenesis leading to hyperpigmentation and manifested
by symmetrical brown to gray-black macules and patches with serrated irregular edges . It
occurs especially in sun-exposed areas and affects young to middle-aged women. It is most
commonly seen on the face and less commonly on the neck, arms, and chest . Platelet rich
plasma (PRP) is defined as a small volume of autologous plasma that contains a high
concentration of platelets obtained by centrifugation of autologous blood and subsequent
suspension of platelets