Efficacy of Intrathecal Administration of Liposomal Amphotericin B in Cryptococcal Meningitis

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The main purpose of this study is to observe the clinical effect of intrathecal administration of liposomal amphotericin B in Cryptococcal Meningitis without Acquired Immune Deficiency Syndrome (AIDS).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hui Bu
• Treatments: Amphotericin B; Liposomal amphotericin B

Criteria

Inclusion Criteria:

• Cryptococcus neoformans are found in CSF

Exclusion Criteria:

• Patients with serious heart, lung, liver and renal insufficiency.

• Patients who took broad-spectrum antibiotics and corticosteroids for a long-term.

• Patients with AIDS or obvious immunodeficiency.

• Patients with long term dialysis or intravenous catheter.

• Patients with other brain organic disease such as purulent meningitis, intracranial swelling, etc.