Efficacy of Iron Fortified Complementary Food and IPT of Malaria in Young Children in Côte d'Ivoire

• Status: Completed
• Trial end date: 2013-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The proposed project is aimed at testing two interventions, namely a highly bioavailable iron compound and a combination of SP plus amodiaquine for intermittent preventive treatment (IPT) of malaria, to reduce anaemia in very young children.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Swiss Federal Institute of Technology
• Collaborators: Swiss National Science Foundation; Swiss Tropical & Public Health Institute
• Treatments: Amodiaquine; Ferrous fumarate; Iron

Criteria

Inclusion Criteria:

• Children, aged 12 - 36 months, both sexes

• Absence of major systemic illnesses (as assessed by medical doctor upon initial full clinical assessment)

• Registered in DSS Taabo and anticipated residence in the study area for at least 1 year

• No severe anaemia, i.e. Hb ≥70 g/L in infants, as assessed by a Coulter Counter device

• No known or reported hypersensitivity to sulfadoxine-pyrimethamine, amodiaquine

• No known or reported history of significant chronic illness

• Written informed consent of parents or legal guardian

Exclusion Criteria:

• severe anaemia, i.e. Hb ≥70 g/L in infants, as assessed by a Coulter Counter device

• major systemic illnesses (as assessed by medical doctor upon initial full clinical assessment)

• known or reported hypersensitivity to albendazole, sulfadoxine-pyrimethamine, amodiaquine

• known or reported history of significant chronic illness