Efficacy of Mefenamic Acid and Hyoscine for Pain Relief During Saline Infusion Sonohysterography in Infertile Women

• Status: Unknown status
• Trial end date: 2010-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The infertility patients who are performed saline infusion sonohysterography (SIS) for studying the pathology inside the uterine cavity has pain. From pilot study the pain score is 6.80. It will have more benefits if we can manage this procedure with less or no pain. Many studies have tried to decrease pain such as types of catheter, intrauterine lidocaine infusion. Some have real effects but no study with oral Mefenamic acid or Hyoscine before the procedure.The drugs are safe and easy to administration and chief.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Collaborator: Siriraj Hospital
• Treatments: Butylscopolammonium Bromide; Mefenamic Acid; Scopolamine; Scopolamine Hydrobromide

Criteria

Inclusion Criteria:

• infertility female

• no history of HSG or Hysteroscopy

Exclusion Criteria:

• vaginal or pelvic infection

• abnormal Pap smear

• contraindications for Mefenamic acid including upper and lower GI ulcers, bleeding disorder, Asthma or allergies, renal disease, using Warfarin,Aspirin, Lithium, history of Mefenamic acid or Hyoscine allergies