Efficacy of Micronized Natural Progesterone vs GnRH Antagonist in the Prevention of LH Peak During Ovarian Stimulation.

• Status: Not yet recruiting
• Trial end date: 2024-09-30
• Target enrollment: 0
• Participant gender: Female

Summary

This study aims to investigate if the use of oral micronized natural progesterone is not inferior to the use of subcutaneous antagonist in preventing LH peak in controlled ovarian stimulation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Instituto Bernabeu
• Treatments: Ganirelix; Progesterone

Criteria

Inclusion Criteria:

• Eligibility for the oocyte donation program at Instituto Bernabeu.

• Age between 18 and 33 years

• BMI >18 and <30

• Overall antral follicle count >8

• Presence of both ovaries

• Ability to participate and comply with the study protocol

• Oral and written comprehension of Spanish

• Having given written consent

Exclusion Criteria:

• Endometriosis at any stage

• Any ovarian tumor whether benign or malignant

• Concurrent participation in another study

• Malabsorptive syndromes that may alter the efficacy of Seidigestan ® such as bariatric surgery, ulcerative colitis or Crohn's disease

• Irregular periods

• Hypogonadotropic hypogonadism

• Having received in the previous two months treatment with ovulation stimulators

• Having previously participated in the present study