Efficacy of Nefopam and Morphine in Balanced Analgesia for Acute Ureteric Colic

• Status: Unknown status
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is to see whether the combination regimen of ketorolac and nefopam is superior to that of ketorolac and morphine in controlling ureter stone-related acute flank pain.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Collaborator: Pharmbio Korea
• Treatments: Analgesics; Ketorolac; Ketorolac Tromethamine; Morphine; Nefopam

Criteria

Inclusion Criteria:

• Acute flank with visual analog pain scale score equal or more than 5

• and most possible diagnosis after initial clinical exam is acute renal colic

Exclusion Criteria:

• Pregnant or lactating women

• Patients whose use of any of the study drugs is contraindicated

• Patients with documented renal or hepatic failure or those with clinical findings suggesting the diagnoses

• Recent episode of acute myocardial infarction or patients with significant heart failure

• Patients with documented gastric/duodenal ulcer or those with clinical findings suggesting the diagnoses

• Patients with bleeding tendency

• Patients who have history of any seizure

• Patients with documented organic brain injury

• Patients taking warfarin

• Patients whose primary diagnosis is not renal colic