Efficacy of Oral Minocycline (Solodyn) and Oral Minocycline (Solodyn) Plus Azelaic Acid (Finacea) for Acne Rosacea

• Status: Completed
• Trial end date: 2011-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Rosacea is one of the most commonly occurring dermatoses treated by dermatologist today. Rosacea is an inflammatory condition of the skin presenting as flushing and or blushing along with redness, swelling, telangiectasia, and acne lesions. Minocycline has shown beneficial in the treatment of inflammatory acne lesions in patients with rosacea. This study is to evaluate the efficacy and tolerability of minocycline (Solodyn) alone versus minocycline (Solodyn) in combination with azelaic acid 15%(Finacea) in the treatment of rosacea.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Dermatology Specialists Research
• Treatments: Azelaic acid; Minocycline

Criteria

Inclusion Criteria:

• age 18 or older with clinical diagnosis of rosacea

• must have 10-40 facial inflammatory lesions and less than 2 nodules

• women of child bearing potential must be non lactating

• must have negative urine pregnancy test

• must use effective form of birth control

Exclusion Criteria:

• The use of systemic antibiotics within 30 days of study start

• the use of topical medications within 14 - 30 days of study start depending on type of topical medication

• Patients with known sensitivity to tetracyclines

• Patients who have had gastric bypass surgery or are considered achlorhydric

• Patients taking drugs known as photosensitizers