Efficacy of Parecoxib Combined With Paracetamol in Mastectomy

• Status: Not yet recruiting
• Trial end date: 2023-05-10
• Target enrollment: 0
• Participant gender: Female

Summary

Patients undergoing breast cancer surgery experience persistent pain after surgery and subsequent development of chronic pain. Parecoxib or paracetamol has been reported to reduce postoperative pain in mastectomy. The investigators aim to assess the effectiveness of the perioperative administration of parecoxib combined with paracetamol to reduce postoperative acute and subacute breast surgical pain.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Khon Kaen University
• Treatments: Acetaminophen; Parecoxib

Criteria

Inclusion Criteria:

• Patients with breast cancer undergoing elective mastectomy

• ASA physical status 1-3

Exclusion Criteria:

• Allergy to parecoxib, paracetamol, or sulfonamide

• History of opioid use

• Pregnant

• Renal or hepatic disease