Efficacy of Peri-neural Platelet Rich Plasma Injection in Treatment of Chemotherapy Induced Peripheral Neuropathy.

• Status: Not yet recruiting
• Trial end date: 2024-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to show the efficacy and safety of ultra-sound guided peri-neural platelet rich injection in treatment of chemotherapy induced peripheral neuropathy.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: South Egypt Cancer Institute

Criteria

Inclusion Criteria:

• cancer patients with peripheral neuropathy confirmed by clinical evaluation and nerve conduction study despite of medical treatment

Exclusion Criteria: patients with:

• Foot ulcers and / or amputation.

• Peripheral vascular disease.

• Uncontrolled diabetes

• Vertebral pathologies.

• Connective tissue diseases.

• Thyriod disorders, significant renal or hepatic dysfunction.

• Platelet dysfunction syndrome, critical thrombocytopenia.

• Septicemia and local infection at the site of the procedure.

• Systemic corticosteriod adminstiration or local injection at the suspected treatment site within the last month.

• Recent fever or illness.

• Hemoglobin level less than 10 g/dl, platelet count less than 105-109/L.