Efficacy of Personalized Exercise Program and Trimetazidine in Rehabilitation of Patients After RFA of AF
Status:
Completed
Trial end date:
2017-04-01
Target enrollment:
Participant gender:
Summary
Atrial fibrillation (AF) is one of the most common forms of heart rhythm disorder in patients
with cardiovascular diseases. The choice of treatment for AF is a complex problem, depending
on the form (paroxysmal, persistent, permanent) of AF, clinical manifestations of cardiac
arrhythmias, associated diseases, the effectiveness of antiarrhythmic drugs. The accumulated
data to date indicate an efficacy of the method of radiofrequency ablation (RFA) in the
treatment of the paroxysmal form of AF. The RFA procedure does not eliminate the pathological
processes that take place during developed AF. This dictates the need to develop and test new
technologies and physical rehabilitation programmes for patients. The positive clinical
effects of physical rehabilitation programmes based on moderate-intensity exercises are well
known. The search for drugs capable of improving the results of RFA for AF in patients
becomes urgent. This creates the prerequisites for the study of the clinical efficacy of
trimetazidine MV in the rehabilitation of patients with cardiac diseases who underwent
treatment of AF with RFA, which will optimize the management of such patients in the
inpatient and outpatient setting.