Efficacy of Piroxicam as a Perioperative Analgesic for Patients Undergoing Fixation of Maxillofacial Fractures
Status:
Unknown status
Trial end date:
2020-05-01
Target enrollment:
Participant gender:
Summary
Patients were allocated randomly by a computer-generated list into two groups: piroxicam
group who received induction with piroxicam(0.4mg/kg) IM and GA group where piroxicam was not
given. Paracetamol IV (24 mg/kg given slowly over 20 minutes) was received by both groups.
After general anesthesia was induced and venous access established, fentanyl 2 micrograms/kg
was given and an appropriate size endotracheal tube was placed intranasal, intubation was
facilitated by Atracurium (0.5 mg/kg). All patients were mechanically ventilated with
pressure-controlled mode with targeted EtCO 2 (30-35 mmHg)and anaesthesia was maintained by 1
MAC Isoflurane in a mixture of 50% air and oxygen in all cases throughout the procedure and
oral pack was introduced.
At the end of the procedure,muscle relaxation was reversed by neostigmine 50 μg/kg and
atropine sulfate 15μg/kg then the endotracheal tube was removed and general anesthesia was
discontinued. Patients were taken to the post anesthesia care unit (PACU).