Efficacy of Pregabalin Versus Combined Pregabalin and Milnacipran in Fibromyalgia.
Status:
Completed
Trial end date:
2019-12-31
Target enrollment:
Participant gender:
Summary
Diagnosis of fibromyalgia is complex and treatment options are limited. Pharmacological
management of fibromyalgia is mainly centered on the central nervous system. In particular
there is robust evidence for the use of tricyclic antidepressants (e.g., amitriptyline),
anti-convulsants such as gabapentin or pregabalin and agents from the serotonin
norepinephrine reuptake inhibitor (SNRI) family such as milnacipran. Aim of the work: To
compare the efficacy of pregabalin agent (averopreg) alone versus combined pregabalin and
serotonin norepinephrine reuptake inhibitor (milnacipran) in the management of fibromyalgia.