Efficacy of Pregabalin for Diabetic Pruritus - A Randomized Controlled Study.
Status:
NOT_YET_RECRUITING
Trial end date:
2026-06-01
Target enrollment:
Participant gender:
Summary
Brief Summary:
The goal of this randomized controlled study is to learn if pregabalin combined with emollients can reduce pruritus (itching) in people with Type 2 Diabetes Mellitus. The main questions it aims to answer are:
Does pregabalin combined with emollients reduce pruritus severity compared to a placebo combined with emollients? What is the impact of pregabalin on the quality of life of participants suffering from diabetic pruritus? we will compare pregabalin plus emollient to a placebo plus emollient to see if pregabalin works better for reducing pruritus.
Participants will:
Receive either pregabalin 75 mg daily along with emollient therapy or a placebo along with emollient therapy.
Visit the clinic at weeks 4, 8, and 12 for follow-up assessments, including:
Pruritus severity using the Visual Analog Scale (VAS) and 5-D Itch Scale. Patient Global Impression of Change (PGIC) to measure overall improvement. This study will help determine if pregabalin, a drug used for neuropathic pain, can be an effective treatment for pruritus in people with diabetes.
Phase:
PHASE4
Details
Lead Sponsor:
Post Graduate Institute of Medical Education and Research, Chandigarh