Efficacy of Preventive Ketamine on Postoperative Pain
Status:
Recruiting
Trial end date:
2021-12-15
Target enrollment:
Participant gender:
Summary
- Although bariatric surgery is mainly performed laparoscopically, analgesic optimization
is still essential to reduce complications and to improve the patients' comfort. In
laparoscopic sleeve gastrectomy, the intraoperative peritoneal instillation of
bupivacaine hydrochloride (30 ml, 0.25%) was known to be safe and effective in reducing
postoperative pain, nausea, and vomiting.
- Furthermore, usage of ketamine both as a pre and post-operative pain management is well
established. Ketamine can be used solely or in combination with other co-adjuvant drugs,
increasing their efficacy. Many therapeutic properties of ketamine have been attributed
to its antagonism mechanism to N-Methyl-D-aspartate receptors.