Efficacy of Propofol or Midazolam Compare to Placebo for Preoperative Medication
Status:
Completed
Trial end date:
2015-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this research is:
To evaluate the sedative (reduces irritability or agitation), anxiolytic (reduces anxiety),
and amnesic (produces temporary lack of recall) effects of propofol or midazolam when
administered for preoperative medication (before administration of drugs that will put
patient to sleep) in comparison to placebo. This study is to test whether the use of the
pre-anesthesia medication measurably reduces anxiety in comparison to receiving no
pre-anesthesia medication prior to orthopedic procedures.
To assess the effect of propofol in comparison to placebo and midazolam on the ability to
recall (memory of):
- when the doctor places the mask on patient's face prior to going to sleep
- recall of 2 pictures
- on your satisfaction with the anesthesia as well as postoperative side effects in
post-anesthesia care unit (PACU) e.g., nausea ,vomiting and sedation.