Overview

Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations

Status:
Recruiting
Trial end date:
2022-02-01
Target enrollment:
Participant gender:
Summary
To evaluate the efficacy of Rapamycin in extended cervicofacial lymphatic malformations in pediatric patients. Rapamycin is administered oral for a 6 month period. The success rate is determined by volume reduction superior to 1/5e of the initial volume measured by MRI, impact on QOL and reduction of bleeding in case of mucosal involvement.
Phase:
Phase 2
Details
Lead Sponsor:
University Hospital, Lille
Collaborator:
Ministry of Health, France
Treatments:
Everolimus
Sirolimus