Efficacy of Ropivacaine Continuous Wound Instillation Versus Single Shot After Spine Fusion Surgery
Status:
Terminated
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
Because local anesthetic infiltration has not been comparated to continuous infusion after
spine fusion surgery, the investigators designed this study to determine whether this
technique could enhance analgesia and improve patient outcome after posterior lumbar
arthrodesis.
The Main Objective of the study is to compare the evolution of the postoperative levels of
pain until J2, in the scheduled lumbar surgery between 2 groups of patients, one receiving an
infiltration "single shot" of local analgesic (Ropivacaïne), one receiving a single shot
infiltration and a continuous infiltration of Ropivacaine during 48 hours.
In both groups the wound was infiltrated with a solution of ropivacaine 0.5% 200 mg/40 mL,
and in one group an infusion of ropivacaine 0.2% 5 mL/h was maintained for 48 h.
The secondary outcomes are the consumption of morphine,the rate of the nausea and the
postoperative vomits, the delay up to the first rise, the quality of the sleep, the duration
of hospital stay and the persistence of residual pain.