Efficacy of Silver Nanoparticle Gel Versus a Common Antibacterial Hand Gel
Status:
Unknown status
Trial end date:
2008-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this pilot study is to compare the antimicrobial efficacy of silver
nanoparticle gel to a commercialized alcohol-based hand gel on bacterial counts isolated from
the hands of 40 volunteers seeded with Serratia marcescens, a surrogate microbial marker.
Specific aims of this study are: Aim #1: Compare the immediate antimicrobial efficacy of a
one-time application of silver nanoparticle gel (SilvaSorb , AcryMed, Inc., Portland, OR)
versus an alcohol-based hand gel (Purell, GoJo Industries, Akron, OH) in reducing transient
bacterial counts isolated from hands seeded with S. marcescens.
Aim # 2: Compare the persistent antimicrobial efficacy of a one-time application of silver
nanoparticle gel (SilvaSorb) versus an alcohol-based hand gel (Purell) over a 10 minute time
frame in producing a persistent reduction on transient bacterial counts isolated from hands
seeded with S. marcescens.
Aim # 3: Compare user acceptability of silver nanoparticle gel (SilvaSorb) versus an
alcohol-based hand gel (Purell) using a self-assessment questionnaire.