Efficacy of Steroid Supplementation After TMJ Rinsing for Pain Management

• Status: Completed
• Trial end date: 2019-01-24
• Target enrollment: 0
• Participant gender: Female

Summary

The hypothesis to be tested is temporomandibular joint (TMJ) rinsing followed by steroid injection is more efficacious than a placebo injection based on standard pain and physical measures that are recorded before and after treatment.

All procedures will be the same as if following normal TMJ arthrocentesis (rinsing) clinical care except that the patient will be randomly assigned to one of two groups: (1) TMJ rinsing followed by the injection of 1 cc (about ¼ of a teaspoon) of the same rinsing solution (this is the placebo) into the jaw joint; or (2) TMJ rinsing followed by the injection of 1 cc (about ¼ teaspoon) of a steroid (5 mg of triamcinolone hexacetonide) into the jaw joint. A pregnancy test (urine test) will be conducted on all women of child-bearing age to verify that the patient is not pregnant before the rinsing procedure. The patient will fill out a short questionnaire and have a short exam of the TMJ and jaw muscles at each appointment.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Florida
• Treatments: Triamcinolone; Triamcinolone Acetonide; Triamcinolone diacetate; Triamcinolone hexacetonide

Criteria

Inclusion Criteria:

• Female

• 18-80 years of age

• TMJ arthralgia

• Masticatory myalgia

• TMJ sounds

• History of at least 6 weeks use of occlusal appliance therapy

Exclusion Criteria:

• Contraindication to sedation including pregnancy or medical history

• History of previous TMJ procedure including arthrocentesis, arthroscopy or arthrotomy

• History of steroidal injection into TMJ

• History of trauma to TMJ

• TMJ pain longer than 3 years

• History of narcotic drug use on a scheduled basis

• Current active infection