Efficacy of Subgingivally Delivered Doxycycline Plus Ketoprofen Gel as an Adjunct to Non-surgical Periodontal Treatment
Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
Objectives: The aim of the present clinical study was to evaluate the efficacy of doxycyline
3% plus ketoprofen 2.5% as an adjunct to scaling and root planing in the treatment of chronic
periodontitis(early-modearte). Material and Methods: 20 systemically healthy, chronic
periodontitis patients were included in the study.The Patients were selected on the basis of
having chronic periodontitis with periodontal pocket depths of more than 4mm on at least two
teeth in mandibular molar area; Periodontal parameters (plaque, bleeding on probing and
pocket depth) were recorded at baseline and every 15 days for 3 months. Oral hygiene
instructions were given that included brushing twice- daily, (Using the Bass brushing
technique for at least 2 minutes ), Randomly divided two groups,Test group: was treated by
scaling and root planing Followed by local delivery of doxycycline 3%+ ketoprofen 2.5%, While
the control group: was treated by scaling and root planing along with ketoprofen 2.5%; and
was administered to the both groups every 15 days for 3 months, repeated. Every 15 days once
periodontal parameters were assessed, and at the end of 3 months, evaluated the clinical
parameters changes.