Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy
Status:
Completed
Trial end date:
2005-09-01
Target enrollment:
Participant gender:
Summary
Patients with Parkinson's Disease or Multiple System Atrophy (MSA), and symptoms of
orthostatic hypotension, are eligible for the study. Each patient will have three weeks of
conservative therapy, three weeks of therapy with fludrocortisone, and three weeks of therapy
with domperidone. Autonomic testing, a symptom questionnaire, bedside blood pressure testing,
and Unified Parkinson Disease Rating Scale (UPDRS) will be performed after each intervention.