Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment
Status:
Unknown status
Trial end date:
2019-05-31
Target enrollment:
Participant gender:
Summary
The aim of the present study is to evaluate the clinical and microbiological efficacy of
moxifloxacin or amoxicillin plus metronidazole in one-stage scaling and root planing in
treating generalized aggressive periodontitis. Forty five subjects will be randomly allocated
to 3 treatment groups. Subgingival plaque samples will be analysed for cultivable bacteria.
The primary outcome variable to determine the superiority of one treatment over the others
would be differences between groups for means CAL changes at 6 months post-treatment.
Secondary outcome variables include differences between therapies for the mean changes in the
mean levels of PD and the proportion of BOP.
Phase:
Phase 4
Details
Lead Sponsor:
Facultad Nacional de Salud Publica
Treatments:
Amoxicillin Fluoroquinolones Metronidazole Moxifloxacin Norgestimate, ethinyl estradiol drug combination