Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis

• Status: Completed
• Trial end date: 2016-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether thymosin alpha 1 is effective on improving monocyte function and has the desired pharmacologic activity for sepsis

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sun Yat-sen University
• Treatments: Thymalfasin

Criteria

Inclusion Criteria:

1. Written informed consent from the patients or their next of kin for patients unable to consent

2. Age ≥18 yrs

3. Presence of sepsis/ septic shock according to sepsis 3.0

Exclusion Criteria:

1. Pregnant or lactation period.

2. Age <18 yrs

3. Receiving immunosuppressive therapy such as cyclosporine, azathioprine or cancer chemotherapy within one month.

4. History of bone marrow, lung, liver, kidney, pancreas or small bowel transplantation;

5. Acute pancreatitis with no established source of infection.

6. Not expected to survive 28 days because of end-stage diseases.

7. Participation in another clinical trial.