Investigation of the therapeutic effects of tolvaptan in patients with autosomal dominant
polycystic kidney disease This is a prospective 5-year study to compare the change in total
kidney volume (TKV) before and after tolvaptan therapy, as the primary endpoint, in patients
with ADPKD. Study results will be summarized, analyzed, and compiled into a research paper at
5 years (data cut-off, Aug 31, 2020).