Efficacy of Topical Cyclosporin for Ocular Rosacea

• Status: Completed
• Trial end date: 2007-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether Restasis (topical cyclosporin) is effective in the treatment of ocular rosacea

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ophthalmic Consultants of Long Island
• Collaborator: Allergan
• Treatments: Cyclosporine; Cyclosporins

Criteria

Inclusion Criteria:

• Patient at least 18 years old, but younger than 65

• Diagnosis of acne rosacea

• Active ocular rosacea based on lid findings of meibomian gland dysfunction with lid telangiectasia and hyperemia of at least 2+

• Schirmers test of greater than 5mm in at least 1 eye

• If patient currently using lid hygiene must maintain regimen during study

• Stop oral antibiotics at least 4 weeks prior

Exclusion Criteria:

• Use of topical cyclosporin within last 90 days

• Visual acuity of 20/100 or better in both eyes

• Pregnant or lactating females

• Active ocular infection

• Scarring of central cornea

• Eyelid defects,abnormal lid positioning or lagophthalmos

• Flax seed or Fish oil supplements within last 30 days