Efficacy of Tranexamic Acid in Reducing Blood Loss During and After Caesarean Section

• Status: Unknown status
• Trial end date: 2015-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to evaluate the efficacy of tranexamic acid in reducing blood loss during and after elective C.S.

The Research Question Is Tranexamic acid effective in reducing blood loss during and after elective Caesarean section?

The Research Hypothesis The TXA could be able to reduce blood loss during and after elective Caesarean section.

The null hypothesis will therefore state that:

There will be no difference between TXA and placebo in reducing blood loss during and after elective Caesarean section.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ain Shams University
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• Pregnant women aged 20-40 with singleton fetus 38 or more weeks

• Uncomplicated pregnancy, up to 3rd parity

• Women undergoing scheduled elective C.S

Exclusion Criteria:

• Causes of uterine over-distention such as polyhydramnios or macrosomia

• Grand multi parity

• Previous PPH (3 x risk) or previous history of retained placenta

• Pre-eclampsia or pregnancy-induced hypertension

• Maternal hypertension

• Pre-existing maternal hemorrhagic conditions

• Maternal diabetes mellitus

• Abnormal placenta

• Sensitivity to TXA

• Women taking anticoagulant therapy