Efficacy of Trans-tympanic Injections of a Sodium Thiosulfate Gel to Prevent Cisplatin-induced Ototoxicity
Status:
Terminated
Trial end date:
2017-01-20
Target enrollment:
Participant gender:
Summary
This study evaluates whether a gel containing sodium thiosulfate deposited via a
trans-tympanic injection on the round window of the middle ear could reduce the ototoxicity
caused by the drug Cisplatin among patients with head and neck cancer treated by
chemoradiation. One ear selected randomly will be treated while the other will serve as
control.
Phase:
Phase 2
Details
Lead Sponsor:
Centre Hospitalier Universitaire de Québec, CHU de Québec CHU de Quebec-Universite Laval