Efficacy of Trypsin-Chymotrypsin On Post-operative Pain After Single Visit Root Canal Treatment

• Status: Completed
• Trial end date: 2021-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Achieving effective pain control after endodontic treatment is still a disruptive event to all the clinicians. There is a knowledge gap regarding the effect of protease on postoperative pain following root canal treatment, therefore, the efficacy of Trypsin-Chymotrypsin on post endodontic pain was evaluated clinically in a randomized triple-blind trial.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Analgesics

Criteria

Inclusion criteria:

• Egyptian healthy symptomatic both gender patients

• aged (18- 40) years old

• with no physical disability, facial paresthesia or psychological problems

• had mandibular first molars with symptomatic irreversible pulpitis and with normal appearance radiographically.

Exclusion criteria:

• The vulnerable group

• participants who un abled to read and fill the questionnaire,

• those who took preoperative analgesics 24 h prior to treatment

• those with known sensitivity to the drugs used in this study