Efficacy of Two Chlorhexidine Solutions to Control the Initial Subgingival Biofilm Formation

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to compare the effect of a suspension containing chlorhexidine and alcohol and another one containing clorhexidine with no alcohol in dynamic of the subgingival biofilm formation versus a Placebo suspension. The initial subgingival biofilm formation will be evaluated by means of Plaque Free Zone (PFZ).

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Federal University of Rio Grande do Sul
• Treatments: Chlorhexidine; Chlorhexidine gluconate; Ethanol

Criteria

Inclusion Criteria:

• age from 18 years;

• non-smokers;

• have good general health;

• present at least 20 natural teeth in the mouth, including the incisors, canines and premolars without restorations, crowns, gingival recession, anatomic defects, gingivitis e/or periodontitis.

Exclusion Criteria:

• • positive history of using antibiotic e/or anti-inflammatory drugs in the month previous to the initial consultation;

• positive history of allergies at using Triclosan;

• pregnant or lactating patients;

• patients in use of fixed orthodontic appliance.