Efficacy of Valsartan/Hydrochlorothiazide Versus Amlodipine and Hydrochlorothiazide in Patients Hypertension

• Status: Completed
• Trial end date: 2007-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the efficacy of valsartan/hydrochlorothiazide versus amlodipine and hydrochlorothiazide in patients with Stage 2 hypertension using 24-hr ambulatory blood pressure monitoring (ABPM)

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Novartis
• Treatments: Amlodipine; Hydrochlorothiazide; Valsartan

Criteria

Inclusion Criteria:

• Male or female patients 18 years of age or older

• Diagnosed of having hypertension, defined as a mean seated systolic BP ≥160 mmHg (Stage 2 hypertension)

Exclusion Criteria:

• Symptomatic or severe hypertension

• Patients treated with more than 2 antihypertensive medications

• Clinically known or suspected history of secondary hypertension

• Myocardial infarction, stroke, transient ischemic attack, cardiovascular revascularization/angioplasty in last 6 months

• Diagnosis of heart failure (NYHA Class II-IV)

• Chronic renal or severe hepatic disease