Efficacy of Vitamin D Supplementation for Children With Bronchiolitis
Status:
Not yet recruiting
Trial end date:
2024-05-01
Target enrollment:
Participant gender:
Summary
Vitamin D plays an important role in enhancing mucosal immune defense, decreasing excessive
inflammation, and increasing mucociliary clearance. Experimental studies have shown that
vitamin D reduces inflammation of epithelial cells in airways infected with Respiratory
Syncytial Virus and confers antiviral effects. Furthermore, several studies have shown lower
serum vitamin D levels in hospitalized children with bronchiolitis. However, studies on the
efficacy of Vitamin D supplementation for children with bronchiolitis are scarce with
inconsistent findings. In this study, we aim to evaluate the efficacy of vitamin D
supplementation in children with bronchiolitis.