Efficacy of Vitamin E in Preventing Contrast-Induced Acute Kidney Injury Following Coronary Angiography

• Status: Completed
• Trial end date: 2015-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the effect of vitamin E on preventing from incidence of contrast induced acute kidney injury (CI-AKI) in the patients who undergone coronary angiography.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Urmia University of Medical Sciences
• Treatments: alpha-Tocopherol; Tocopherols; Tocotrienols; Vitamin E; Vitamins

Criteria

Inclusion Criteria:

1. All patients whon have either stable coronary artery disease (CAD) or recent acute coronary disease (ACS) and are scheduled for coronary angiography.

2. Patients who have eGFR ≤60 ml/min/1.73 m2

Exclusion Criteria:

1. Allergy to contrast media

2. Cardiogenic shock

3. Pulmonary edema

4. Overt cardiac failure or left ventricular ejection fraction ≤ 30%

5. Acute kidney injury

6. The history of receiving contrast media for any medical diagnostic or therapeutic procedures during previous 5 days

7. The history of dialysis

8. Being pregnant

9. Having recent acute myocardial infarction

10. Taking antioxidants and nephrotoxic drugs including NSAID and ACE-I on previous 2 days