Efficacy of a Probiotic Lozenges in Chronic Periodontitis Patients.

• Status: Completed
• Trial end date: 2016-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Periodontal disease is an infectious disease resulting in inflammation within supporting tissues of the teeth, progressive attachment loss, and bone loss. Epidemiological studies reveal that about 10% of the adult population suffer from severe periodontitis.It comprises of two distinct but interconnected etiologic components: the periodontopathic bacteria adjacent to the periodontal tissues, and the host-mediated connective tissue-destructive responses to the causative bacteria and their metabolic products. In the arena of periodontics, the probiotics pose a great potential of plaque modification, halitosis management, altering anaerobic bacteria colonization, improvement of pocket depth, and clinical attachment gain.

Aim of the study is to analyze the beneficial effect of probiotic lozenges as an adjunct to Scaling and Root Planing, on clinical and biochemical parameters.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: CD Pharma India Pvt. Ltd.
• Collaborator: Government Dental College and Hospital, India

Criteria

Inclusion Criteria:

• Subject of both sexes

• Age group of 25-65 years

• Subjects with generalized moderate to severe chronic periodontitis

• Signed informed Consent

Exclusion Criteria:

• Any known history of systemic diseases

• Patients already on anti-inflammatory drugs or antibiotics

• Patients allergic to any material used in the study

• Pregnant and lactating women

• Periodontal therapy in past 6 months

• Current smoker or smoker in the past