Eggs for Gut Health

• Status: Recruiting
• Trial end date: 2024-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical trial is to test egg powder supplementation in children with moderate acute malnutrition in Sierra Leone. The main question it aims to answer is:

• Will provision of 15g of whole egg powder per day during and after treatment for moderate acute malnutrition (for 24 weeks total) improve small intestinal permeability and linear growth among 6-30 month old Sierra Leonean children compared with daily corn powder supplementation?

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Washington University School of Medicine
• Collaborators: Ministry of Health and Sanitation, Sierra Leone; Project Peanut Butter; Thrasher Research Fund
• Treatments: Fanasil, pyrimethamine drug combination; Micronutrients; Pyrimethamine; Sulfadoxine; Trace Elements

Criteria

Inclusion Criteria:

• At least 6 months of age and less than 30 months of age

• Mid-upper arm circumference >= 11.5cm and < 12. 5 cm

• Mid-upper arm circumference-for-age z-score < -2

• Provision of signed (or thumb-printed) and dated informed consent form

• Stated willingness to comply with all study procedures and availability for the duration of the study, including no plan to move from the catchment area of a participating clinic

Exclusion Criteria:

• Nutritional edema

• Simultaneous involvement in another research trial or supplementary feeding program

• Chronic debilitating illness

• Allergy to egg

• Receipt of treatment for acute malnutrition within 1 month prior to screening