Electroacupuncture Therapy for Treating Postherpetic Neuralgia

• Status: Recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Postherpetic neuralgia (PHN) has a high incidence rate and severely impact on quality of life and health care costs, interfering with physical, emotional and social functioning of affected patients. Current therapeutic options for PHN mainly include analgetic and local anaesthesia for selective nerve blockade. Nevertheless, the efficacy of analgetic is always limited by inevitable side effects, in which patients have poor compliance. Moreover, for some most suffering patients, the control of pain is often unsatisfactory despite the administration of complex combinations. As a non-pharmarceutical therapy, acupuncture is widely use for a wide range of pain conditions. Thus, it might be an alternative treatment for PHN. The aim of this multicenter randomized controlled trial is to investigate the efficacy and safety of electroacupuncture therapy in patients with postherpetic neuralgia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Third Affiliated hospital of Zhejiang Chinese Medical University
• Collaborators: Lishui Hospital of Traditional Chinese Medicine; The First Affiliated Hospital of Zhejiang Chinese Medical University; Zhejiang Provincial Tongde Hospital

Criteria

Inclusion Criteria:

1. Patients have a medical history of herpes zoster;

2. Skin lesion has healed in the region of herpes zoster, but the duration of postherpetic neuralgia persist for more than 30 days.

3. 20 ≤ age ≤80 years, male or female

4. Participants can fully understand the study protocol and written informed consent is signed.

Exclusion Criteria:

1. Acute herpes zoster, herpes zoster has not disappeared;

2. Herpes zoster belongs to a special type, such as ophthalmic herpes zoster, auricular herpes zoster, HZ that involves internal organs, meningeal herpes zoster, and disseminated herpes zoster.

3. Pregnant or lactating women;

4. Patients have severe complications in cardiovascular, cerebrovascular, liver, kidney, hematopoietic and other systems,or have malignant tumor, mental illness, immune deficiency, hemorrhagic disorders and other diseases;

5. Patients have severe cognitive impairment and can not understand the study protocol;

6. Patients can not receive electroacupuncture treatment due to any reasons.