Electronic Cigarettes in Daily Dependent Smokers

• Status: Completed
• Trial end date: 2015-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to measure nicotine cue- and withdrawal-induced craving in current smokers under four distinct conditions: after smoking a conventional cigarette, an electronic cigarette (e-Cigarette) containing nicotine, an e-Cigarette without nicotine, and after taking a nicotine lozenge. Participants will be asked to attend four morning study visits after overnight smoking abstinence. Standardized questionnaires will be used to assess changes under each condition, allowing for the investigation of the efficacy of e-Cigarettes in reducing craving by replacing the behavioral component of smoking with minimal risk of adverse effects.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre for Addiction and Mental Health
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• Current daily smoker

• Smoke minimum of 10 cigarettes per day

• Fagerstrom Test of Nicotine Dependence Score equal or greater than 3

• Never used an e-Cigarette prior to the study

• No intention to quit smoking within the next 3 months

• Able to provide written informed consent

• Able and willing to attend scheduled appointments

Exclusion Criteria:

• Any serious medical or unstable psychiatric problems requiring treatment

• Pregnancy or lactation