EMLA is proven to be better in achieving pain control as topical anesthesia than benzocaine
at palatal mucosa. So this research is done to compare its effectiveness at buccal mucosa.
Methods:
A total number of 70 patients attending DOW ojha hospital, fulfilling inclusion criteria and
undergoing extraction of bilateral teeth will be included in this study. Approval of data
collection will be sought from the Institutional ethical review board ¬(IERB) of Dow
university of health sciences (DUHS) for this study. the participants will be briefed about
the nature and purpose of the study including visual analogue scale (VAS). They will be
ensured that their information will be used for the study purpose only. Informed consent from
the participants will be obtained. Complete history from patients will be taken. The sites
will be divided into condition A- 5% EMLA and Condition B - 20% Benzocaine Gel. After marking
injection sites, principal investigator will leave the room and the consultant will apply 5%
EMLA gel at experimental area and 20% Benzocaine gel at control area. After pre-treatment
with topical anesthesia the consultant will administer local anesthesia to both sides. Then
Principal investigator will be signaled into the room and patient will be assessed though
visual analogue scale by him and will be confirmed by supervisor.
Phase:
Early Phase 1
Details
Lead Sponsor:
Dow University of Health Sciences
Treatments:
Benzocaine Lidocaine Lidocaine, Prilocaine Drug Combination Prilocaine