Emotion, Mood and Executive Function in Parkinson's Disease (PD)

• Status: Unknown status
• Trial end date: 2013-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The current study aims to assess the effect of an 8 week Azilect treatment (as adjunct therapy to levodopa) on affect perception and emotional expressiveness in a double-blind placebo-controlled study.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: St. Josef Hospital Bochum
• Treatments: Rasagiline

Criteria

Inclusion Criteria:

• idiopathic PD

• age range 30-75 yrs, HY I-III

• stable medication for at least 4 weeks prior to baseline

• Native speakers (German)

• signing of informed consent form

Exclusion Criteria:

• clinically significant depression (BDI>13)

• freezing, pronounced fluctuations

• other neurological or psychiatric disorders

• dementia (MMSE<25)

• treatment with the MAO-B-inhibitor Selegiline, antidepressants

• any contraindication according to SmPC

• participation in another interventional study