Emotional Effects of Methylphenidate and MDMA in Healthy Subjects
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
This study compares the interactive emotional/subjective effects of single doses of
3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") and methylphenidate, a dopamine (DA) and
norepinephrine (NE) transporter blocker, in healthy subjects. The primary goal is to
determine the role of transporter mediated DA and NE release in the subjective response to
MDMA in humans. The investigators hypothesize that methylphenidate will attenuate the
subjective response to MDMA.