Enbrel Versus Placebo With Radiation Therapy to Combat Fatigue and Cachexia

• Status: Terminated
• Trial end date: 2005-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients who receive radiation therapy often have fatigue or a decrease in feeling well causing a "wasting" away. For patients with advanced disease of lung cancer, prostate cancer, or cancer that has spread to the bone, it is hoped that this drug may decrease this. If patients feel better during treatments they can complete the therapy without any breaks in treatment. For treatment to be most effective, it should be given in the amount needed, on a particular schedule.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Texas Health Science Center at San Antonio
• Collaborator: Sanchez Cancer Center
• Treatments: Etanercept

Criteria

Inclusion Criteria:

• Advanced lung, prostate, or bony metastasis for cancer

• Performance status (PS) of 3 or less

• Good lab test results with albumin of at least 2.5

• Radiation therapy of at least 4000Gy in 4 weeks

Exclusion Criteria:

• Poor PS

• Planned radiation therapy for less than 4 weeks or 4000Gy

• Limited disease