Endocrine Response of the Organism to Polytrauma

• Status: Recruiting
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The serious injury causes a complex acute response of the organism to the injury in affected patients, which is manifested in the neuroendocrine, immune and metabolic areas, with an often persisting catabolic state, with a subsequent negative impact upon bone metabolism.

By a timely administration of the D3 vitamin and an anabolic, we attempt to achieve an earlier activation of the anabolic phase of patient resuscitation after serious trauma regarding the monitoring of laboratory values of bone metabolism.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Ostrava
• Treatments: Cholecalciferol; Ergocalciferols; Testosterone Congeners; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• serious polytrauma with ISS>31b

• females, 18-50 years of age

• males, 18-60 years of age

• signed informed consent with participation in the study

Exclusion Criteria:

• infaust craniocerebral injury

• gravidity

• lactation

• prostate cancer