Overview

Endocrine Therapy With Abemaciclib or Chemotherapy as Initial Metastatic Treatment in ER+/HER2- Breast Cancer

Status:
Recruiting
Trial end date:
2026-06-01
Target enrollment:
Participant gender:
Summary
AMBRE is a phase III study comparing two standard treatments as initial metastatic treatment in ER+/HER2- breast cancer (BC) patients with visceral metastasis and high burden disease: Chemotherapy and combination of endocrine therapy with abemaciclib.
Phase:
Phase 3
Details
Lead Sponsor:
UNICANCER
Treatments:
Albumin-Bound Paclitaxel
Anastrozole
Aromatase Inhibitors
Capecitabine
Fulvestrant
Letrozole
Paclitaxel