Endometrial Effects of Metformin Action in Women With Polycystic Ovarian Syndrome (PCOS)
Status:
Completed
Trial end date:
2013-07-01
Target enrollment:
Participant gender:
Summary
The investigators aim is to conduct a prospective un-blinded pilot study of premenopausal
women diagnosed with Polycystic Ovarian Syndrome (PCOS), defined using criteria developed at
the 1990 NICHD conference on PCOS, undergoing treatment for ovulation induction with
Metformin. We propose that improving insulin sensitivity with use of Metformin in women
diagnosed with PCOS has facilitatory influences on the uterine endometrium.
Details
Lead Sponsor:
Yale University
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)