Endotherapy for Painless Chronic Pancreatitis

• Status: Recruiting
• Trial end date: 2023-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a prospective randomized controlled trial. . Patients will be divided into conservative or endoscopic group and fecal pancreatic elastase-1 (FE-1) is tested to evaluate pancreatic exocrine function. The effect of extracorporeal shock wave lithotripsy and endoscopic treatment on the progression of chronic pancreatitis in painless patients will be determined.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Changhai Hospital
• Treatments: Acarbose; Hypoglycemic Agents; Metformin; Pancreatin; Pancrelipase

Criteria

Inclusion Criteria:

• diagnosed with chronic pancreatitis without pain attack related with chronic pancreatitis;

• calcified stone in the cephalic or corporeal portion of the main pancreatic duct with upstream duct dilation;

• no ERCP or ESWL carried out before admission;

Exclusion Criteria:

• suspected to have malignant tumors;

• history of pancreatic surgery or gastrojejunostomy (Billroth II);

• with end-stage disease;

• pregnancy or lactation;

• refuse to write informed consent